Synthetic Neurons Open the Door for More Intelligent Robots
February 13, 2025

An interdisciplinary collaboration between Northwestern University and Georgia Tech has created a novel high-performance organic electrochemical neuron that responds within the frequency range of human neurons. The researchers also built a complete perception system by designing other organic materials and integrating their engineered neurons with artificial touch receptors and synapses, which enabled real-time tactile signal sensing and processing.
The background
Artificially engineered biological processes, such as perception systems, have been an elusive target for organic electronics experts due to the reliance of human senses on an adaptive network of sensory neurons, which communicate by firing in response to environmental stimuli.
Why it matters
The research, described in a paper in the journal Proceedings of the National Academy of Sciences, could move the needle on intelligent robots and other systems currently stymied by sensing systems that are less powerful than those of a human.
“The study highlights significant progress in organic electronics and their application in bridging the gap between biology and technology,” said first author Yao Yao, a Northwestern engineering professor. “We created an efficient artificial neuron with reduced footprint and outstanding neuronal characteristics. Leveraging this capability, we developed a complete tactile neuromorphic perception system to mimic real biological processes.”
‘Outstanding’ characteristics
According to corresponding author Tobin J. Marks, Northwestern’s Charles E. and Emma H. Morrison Professor of Chemistry in the Weinberg College of Arts and Sciences, existing artificial neural circuits tend to fire within a narrow frequency range.
“The synthetic neuron in this study achieves unprecedented performance in firing frequency modulation, offering a range 50 times broader than existing organic electrochemical neural circuits,” Marks said. “In contrast, our device’s outstanding neuronal characteristics establish it as an advanced achievement in organic electrochemical neurons.”
Marks is a world leader in the fields of organometallic chemistry, chemical catalysis, materials science, organic electronics, photovoltaics and nanotechnology. He is also a professor of Materials Science and Engineering and Professor of Chemical and Biological Engineering in Northwestern’s McCormick School of Engineering and a Professor of Applied Physics.
“This study presents the first complete neuromorphic tactile perception system based on artificial neurons, which integrates artificial tactile receptors and artificial synapses,” said corresponding author Antonio Facchetti, a professor at Georgia Tech’s School of Materials Science and Engineering and an adjunct professor of chemistry at Northwestern. “It demonstrates the ability to encode tactile stimuli into spiking neuronal signals in real time and further translate them into post-synaptic responses.”
What’s next
With the human brain’s immense network of 86 billion neurons poised to fire, sensing systems remain difficult to recreate. Scientists are limited by both the footprint of the design and by the amount they can create. In future models, the team hopes to further reduce the device’s size, taking the project a step closer to fully mimicking human sensing systems.
Story posted on Northwestern Now, written by Win Reynolds.

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